名稱 | Human ADORA1/CHO |
型號(hào) | CBP71347 |
報(bào)價(jià) | ![]() |
特點(diǎn) | Human ADORA1/CHO 凍存條件:90% FBS+10% DMSO |
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電話:4008750250
號(hào)碼:
手機(jī):18066071954
地址:南京市棲霞區(qū)緯地路9號(hào)
Email: zhangxiangwen@cobioer.com
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藥靶細(xì)胞株 > GPCR細(xì)胞株 > CBP71347Human ADORA1/CHO

- 詳細(xì)內(nèi)容
CBP71347 | |
I. Background | |
ADORA1 is a receptor for adenosine. It is demonstrated that the ADORA1 receptor is ubiquitous throughout the entire body. Activation of ADORA1 elicits an inhibition of adenylate cyclase and therefore a decrease in the cAMP concentration. ADORA1 receptors are implicated in sleep promotion by inhibiting wake promoting cholinergic neurons in the basal forebrain. Adenosine antagonists are widely used in neonatal medicine. | |
II. Introduction | |
Host Cell: | CHO |
Stability: | 20 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Freeze Medium: | 90% FBS+10% DMSO |
Culture Medium: | F12k+10%FBS+5ug/ml puromycin |
Mycoplasma Status: | Negative |
Storage: | Liquid nitrogen immediately upon delivery |
Application(s): | Functional assay for A1 receptor |
Transducer: | Gi |
Ⅲ. Description of Host Cell Line | |
Organism: | Hamster |
Tissue: | Ovary |
Morphology: | Epithelial |
Growth Properties: | Adherent |
Ⅳ. Representative Data | |
Figure 1. NECA efffect on CHO-K1-ADORA1 clone 5. |