| 名稱 | PIK3CA p.E545G Reference Standard 標(biāo)準(zhǔn)品 |
| 型號(hào) | CBP10543 |
| 報(bào)價(jià) |  |
| 特點(diǎn) | PIK3CA p.E545A Reference Standard |
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電話：4008750250
號(hào)碼：
手機(jī)：18066071954
地址：南京市棲霞區(qū)緯地路9號(hào)
Email： zhangxiangwen@cobioer.com
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基因檢測(cè)標(biāo)準(zhǔn)品 > Mutation > CBP10543PIK3CA p.E545G Reference Standard 標(biāo)準(zhǔn)品
- 詳細(xì)內(nèi)容
| CBP10543 | |
| Format | Genomic DNA |
| Description | PIK3CA E545G is a hotspot mutation that lies within the PIK helical domain of the Pik3ca protein (UniProt.org). E545G confers a gain of function on the Pik3ca protein as demonstrated by increased phosphorylation of Akt and transformation in cell culture (PMID: 17376864, PMID: 29533785). |
| Technical Data | |
| DNA Change: | c.1634A>G |
| AA Change | p.E545G |
| Mutation type | Substitution - Missense |
| Zygosity | Heterozygous |
| Allelic Frequency | 50% |
| Transcript | NM_006218 |
| Cosmic ID | COSM764 |
| Chr position(GRCh37) | chr3:178936092 |
| Buffer: | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purity | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing | Download for COA |
| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
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